Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM67751
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
>10000±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM67751
Synonyms:
4-(6,7-diethoxy-4-keto-2-thioxo-1H-quinazolin-3-yl)piperidine-1-carboxylic acid ethyl ester | 4-(6,7-diethoxy-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)-1-piperidinecarboxylic acid ethyl ester | MLS000095446 | SMR000031000 | cid_3237801 | ethyl 4-(6,7-diethoxy-4-oxidanylidene-2-sulfanylidene-1H-quinazolin-3-yl)piperidine-1-carboxylate | ethyl 4-(6,7-diethoxy-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)piperidine-1-carboxylate | ethyl 4-(6,7-diethoxy-4-oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)piperidine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C20H27N3O5S
Mol. Mass.:
421.51
SMILES:
CCOC(=O)N1CCC(CC1)n1c(=S)[nH]c2cc(OCC)c(OCC)cc2c1=O
Structure:
Search PDB for entries with ligand similarity: