Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68006
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
470±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68006
Synonyms:
Biphenyl-4-carboxylic acid N'-(naphthalene-1-carbonyl)-hydrazide | MLS000562286 | N'-(4-phenylbenzoyl)naphthalene-1-carbohydrazide | N'-(4-phenylphenyl)carbonylnaphthalene-1-carbohydrazide | N'-[oxo-(4-phenylphenyl)methyl]-1-naphthalenecarbohydrazide | SMR000176630 | cid_3127351
Type:
Small organic molecule
Emp. Form.:
C24H18N2O2
Mol. Mass.:
366.4119
SMILES:
O=C(NNC(=O)c1cccc2ccccc12)c1ccc(cc1)-c1ccccc1
Structure:
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