Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68036
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
390±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68036
Synonyms:
(E)-3-(5-nitro-2-thienyl)-N-(o-tolyl)acrylamide | (E)-N-(2-methylphenyl)-3-(5-nitro-2-thiophenyl)-2-propenamide | (E)-N-(2-methylphenyl)-3-(5-nitrothiophen-2-yl)prop-2-enamide | MLS000722291 | SMR000235996 | cid_6031825
Type:
Small organic molecule
Emp. Form.:
C14H12N2O3S
Mol. Mass.:
288.322
SMILES:
Cc1ccccc1NC(=O)\C=C\c1ccc(s1)[N+]([O-])=O
Structure:
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