Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM63909
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
490±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM63909
Synonyms:
3-[[4-[6-(3-chloroanilino)-4-pyrimidinyl]-2-pyrimidinyl]amino]-1-propanol | 3-[[4-[6-(3-chloroanilino)pyrimidin-4-yl]pyrimidin-2-yl]amino]propan-1-ol | 3-[[4-[6-[(3-chlorophenyl)amino]pyrimidin-4-yl]pyrimidin-2-yl]amino]propan-1-ol | MLS000911535 | SMR000463551 | cid_16746083
Type:
Small organic molecule
Emp. Form.:
C17H17ClN6O
Mol. Mass.:
356.809
SMILES:
OCCCNc1nccc(n1)-c1cc(Nc2cccc(Cl)c2)ncn1
Structure:
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