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Target
Neurotensin receptor type 1
Ligand
BDBM79515
Substrate
n/a
Meas. Tech.
Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1
EC50
30200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of Image-Based HTS for Selective Agonists for NTR1 PubChem Bioassay (2011)[AID] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM79515
Synonyms:
Furan-2-carboxylic acid [4-(1-cyclopropanecarbonyl-2-methyl-2,3-dihydro-1H-indol-5-yl)-5-methyl-thiazol-2-yl]-amide | MLS000034235 | N-[4-(1-cyclopropylcarbonyl-2-methyl-2,3-dihydroindol-5-yl)-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide | N-[4-[1-(cyclopropanecarbonyl)-2-methyl-2,3-dihydroindol-5-yl]-5-methyl-1,3-thiazol-2-yl]furan-2-carboxamide | N-[4-[1-(cyclopropanecarbonyl)-2-methyl-indolin-5-yl]-5-methyl-thiazol-2-yl]-2-furamide | N-[4-[1-[cyclopropyl(oxo)methyl]-2-methyl-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-furancarboxamide | SMR000007523 | cid_653059
Type:
Small organic molecule
Emp. Form.:
C22H21N3O3S
Mol. Mass.:
407.485
SMILES:
CC1Cc2cc(ccc2N1C(=O)C1CC1)-c1nc(NC(=O)c2ccco2)sc1C
Structure:
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