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Target
Integrin alpha-L
Ligand
BDBM79609
Substrate
n/a
Meas. Tech.
Dose Response of Developing T Cell Immune Modulators with powder sourced compounds
EC50
9016±n/a nM
Citation
 PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay (2011)[AID] 
Target
Name:
Integrin alpha-L
Synonyms:
CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15
Type:
Enzyme Catalytic Domain
Mol. Mass.:
128317.79
Organism:
Mus musculus
Description:
P24063
Residue:
1162
Sequence:
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGEGDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVAHVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIFASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGHAVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGAPLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVGAPLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVGAEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQKVGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENENSSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDHNMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPIVFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPLAVPGEETKDMGCLEPLRESDKD
  
Inhibitor
Name:
BDBM79609
Synonyms:
5-chloranyl-2-(4-piperidin-1-ylcarbonylphenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione | 5-chloro-2-[4-(piperidine-1-carbonyl)phenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione | 5-chloro-2-[4-(piperidine-1-carbonyl)phenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-quinone | 5-chloro-2-[4-[oxo(1-piperidinyl)methyl]phenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione | VU0125199-5 | cid_659809
Type:
Small organic molecule
Emp. Form.:
C20H21ClN2O3
Mol. Mass.:
372.845
SMILES:
Oc1c2CC=C(Cl)Cc2c(O)n1-c1ccc(cc1)C(=O)N1CCCCC1 |t:4|
Structure:
Search PDB for entries with ligand similarity: