Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM78626
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM78626
Synonyms:
2-Amino-4-methyl-thiazole-5-carboxylic acid (1H-indol-3-ylmethylene)-hydrazide | 2-amino-N'-[(Z)-3-indolylidenemethyl]-4-methyl-5-thiazolecarbohydrazide | 2-amino-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-1,3-thiazole-5-carbohydrazide | 2-amino-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-thiazole-5-carbohydrazide | 2-azanyl-N'-[(Z)-indol-3-ylidenemethyl]-4-methyl-1,3-thiazole-5-carbohydrazide | MLS000525734 | SMR000116208 | cid_6537515
Type:
Small organic molecule
Emp. Form.:
C14H13N5OS
Mol. Mass.:
299.351
SMILES:
Cc1nc(N)sc1C(=O)NN=Cc1c[nH]c2ccccc12 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: