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Target
Bcl-2-related protein A1
Ligand
BDBM78673
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
>20000±0 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM78673
Synonyms:
6-[1,3-bis(oxidanylidene)isoindol-2-yl]-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)hexanamide | MLS000698275 | N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)hexanamide | N-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-6-(1,3-dioxo-2-isoindolyl)hexanamide | N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-6-(1,3-dioxoisoindol-2-yl)hexanamide | N-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-6-phthalimido-hexanamide | SMR000225552 | cid_3524504
Type:
Small organic molecule
Emp. Form.:
C25H26N4O4
Mol. Mass.:
446.4983
SMILES:
Cc1c(NC(=O)CCCCCN2C(=O)c3ccccc3C2=O)c(=O)n(-c2ccccc2)n1C
Structure:
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