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Target
Bcl-2-related protein A1
Ligand
BDBM51882
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
3440±157 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM51882
Synonyms:
2-(diethylamino)ethyl 4-[[(Z)-2-cyano-2-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]ethenyl]amino]benzoate | 4-[[(Z)-2-cyano-2-[4-(3,4-dimethoxyphenyl)-2-thiazolyl]ethenyl]amino]benzoic acid 2-(diethylamino)ethyl ester | 4-[[(Z)-2-cyano-2-[4-(3,4-dimethoxyphenyl)thiazol-2-yl]vinyl]amino]benzoic acid 2-(diethylamino)ethyl ester | 4-{(Z)-2-Cyano-2-[4-(3,4-dimethoxy-phenyl)-thiazol-2-yl]-vinylamino}-benzoic acid 2-diethylamino-ethyl ester | MLS000769345 | SMR000434079 | cid_16682517
Type:
Small organic molecule
Emp. Form.:
C27H30N4O4S
Mol. Mass.:
506.617
SMILES:
CCN(CC)CCOC(=O)c1ccc(cc1)N=CC(C#N)c1nc(cs1)-c1ccc(OC)c(OC)c1 |w:16.16|
Structure:
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