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Target
Bcl-2-related protein A1
Ligand
BDBM79010
Substrate
n/a
Meas. Tech.
Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50
4030±245 nM
Citation
 PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:
Apoptosis regulator protein
Mol. Mass.:
19909.74
Organism:
Mus musculus (Mouse)
Description:
gi_11024684
Residue:
172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
  
Inhibitor
Name:
BDBM79010
Synonyms:
3-(4-chlorobenzyl)-5-methoxy-1-methyl-pyrido[2,3-d]pyrimidine-2,4-quinone | 3-[(4-chlorophenyl)methyl]-5-methoxy-1-methyl-pyrido[2,3-d]pyrimidine-2,4-dione | 3-[(4-chlorophenyl)methyl]-5-methoxy-1-methylpyrido[2,3-d]pyrimidine-2,4-dione | MLS001166793 | SMR000641466 | cid_18567276
Type:
Small organic molecule
Emp. Form.:
C16H14ClN3O3
Mol. Mass.:
331.754
SMILES:
COc1ccnc2n(C)c(=O)n(Cc3ccc(Cl)cc3)c(=O)c12
Structure:
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