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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80458
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
814±79 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80458
Synonyms:
(1E,2E)-3-(2-nitrophenyl)acrylaldehyde (4,6-dipiperidin-1-yl-1,3,5-triazin-2-yl)hydrazone | (4,6-dipiperidino-s-triazin-2-yl)-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]amine | MLS000723636 | N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]-4,6-bis(1-piperidinyl)-1,3,5-triazin-2-amine | N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]-4,6-di(piperidin-1-yl)-1,3,5-triazin-2-amine | SMR000305231 | cid_16189284
Type:
Small organic molecule
Emp. Form.:
C22H28N8O2
Mol. Mass.:
436.5101
SMILES:
[O-][N+](=O)c1ccccc1CC=CN=Nc1nc(nc(n1)N1CCCCC1)N1CCCCC1 |w:13.14,11.12|
Structure:
