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Target
DNA dC->dU-editing enzyme APOBEC-3A
Ligand
BDBM80405
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Temperature
298.15±n/a K
IC50
1660±n/a nM
Comments
extracted
Citation
 PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:
ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23013.77
Organism:
Homo sapiens (Human)
Description:
gi_21955158
Residue:
199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
  
Inhibitor
Name:
BDBM80405
Synonyms:
1-methyl-3-phenyl-6,7,8,9-tetrahydro-5H-imidaz[1,2-a]azepin-1-ium;iodide | 1-methyl-3-phenyl-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-1-ium;iodide | MLS000565397 | SMR000152574 | cid_9551989
Type:
Small organic molecule
Emp. Form.:
C15H19N2
Mol. Mass.:
227.3242
SMILES:
C[n+]1cc(-c2ccccc2)n2CCCCCc12
Structure:
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