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Target
C-C chemokine receptor type 6
Ligand
BDBM79996
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
18200±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM79996
Synonyms:
1-(4-Difluoromethoxy-phenyl)-pyrrole-2,5-dione | 1-[4-(difluoromethoxy)phenyl]-3-pyrroline-2,5-quinone | 1-[4-(difluoromethoxy)phenyl]pyrrole-2,5-dione | 1-[4-[bis(fluoranyl)methoxy]phenyl]pyrrole-2,5-dione | MLS000559359 | SMR000178049 | cid_886511
Type:
Small organic molecule
Emp. Form.:
C11H7F2NO3
Mol. Mass.:
239.175
SMILES:
FC(F)Oc1ccc(cc1)N1C(=O)C=CC1=O |c:14|
Structure:
Search PDB for entries with ligand similarity: