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Target
C-C chemokine receptor type 6
Ligand
BDBM72680
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
14900±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM72680
Synonyms:
5-[5-(4-Chloro-phenyl)-pyrazolidin-3-ylidene]-1,3-dimethyl-pyrimidine-2,4,6-trione | 5-[5-(4-chlorophenyl)-3-pyrazolidinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-barbituric acid | MLS000762999 | SMR000439471 | cid_6224486
Type:
Small organic molecule
Emp. Form.:
C15H15ClN4O3
Mol. Mass.:
334.758
SMILES:
CN1C(=O)C(C2CC(N=N2)c2ccc(Cl)cc2)C(=O)N(C)C1=O |c:8|
Structure:
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