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Target
Tropomyosin alpha-1 chain
Ligand
BDBM80829
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
IC50
12683±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay (2011)[AID] 
Target
Name:
Tropomyosin alpha-1 chain
Synonyms:
TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32681.01
Organism:
Sus scrofa
Description:
P42639
Residue:
284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
  
Inhibitor
Name:
BDBM80829
Synonyms:
3-[(9-amino-7-ethoxy-3-acridinyl)azo]pyridine-2,6-diamine | 3-[(9-amino-7-ethoxyacridin-3-yl)diazenyl]pyridine-2,6-diamine | 3-[(9-azanyl-7-ethoxy-acridin-3-yl)diazenyl]pyridine-2,6-diamine | MLS002701850 | SMR001565442 | [6-amino-3-(9-amino-7-ethoxy-acridin-3-yl)azo-2-pyridyl]amine | cid_434695
Type:
Small organic molecule
Emp. Form.:
C20H19N7O
Mol. Mass.:
373.4112
SMILES:
CCOc1ccc2nc3cc(ccc3c(N)c2c1)\N=N\c1ccc(N)nc1N
Structure:
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