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Target
cAMP-dependent protein kinase type I-alpha regulatory subunit
Ligand
BDBM81294
Substrate
n/a
Meas. Tech.
Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex
EC50
>113704±n/a nM
Citation
 PubChem, PC Counterscreen for activators of the Protein Kinase A-R2B (PKA-R2B) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R1A (PKA-R1A) complex PubChem Bioassay (2011)[AID] 
Target
Name:
cAMP-dependent protein kinase type I-alpha regulatory subunit
Synonyms:
KAP0_BOVIN | PRKAR1A | cAMP-dependent protein kinase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42885.14
Organism:
Bos taurus
Description:
gi_115496662
Residue:
380
Sequence:
MASGTTASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAGSRADSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
  
Inhibitor
Name:
BDBM81294
Synonyms:
3-[(2,4-dichlorobenzyl)sulfanyl]-2-thiophenecarboxylic acid | 3-[(2,4-dichlorobenzyl)thio]-2-thenoic acid | 3-[(2,4-dichlorophenyl)methylsulfanyl]thiophene-2-carboxylic acid | 3-[(2,4-dichlorophenyl)methylthio]-2-thiophenecarboxylic acid | MLS000328052 | SMR000168585 | cid_1480284
Type:
Small organic molecule
Emp. Form.:
C12H8Cl2O2S2
Mol. Mass.:
319.227
SMILES:
OC(=O)c1sccc1SCc1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: