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Target
D(2) dopamine receptor
Ligand
BDBM50017679
Substrate
n/a
Ki
140±n/a nM
Comments
PDSP_1477
Citation
 Burt, DR; Creese, I; Snyder, SH Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes. Mol Pharmacol 12:800-12 (1976) [PubMed] 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50017679
Synonyms:
Benzyl-(2-chloro-ethyl)-(1-methyl-2-phenoxy-ethyl)-amine | CHEMBL753 | Dibenzyline | PHENOXYBENZAMINE
Type:
Small organic molecule
Emp. Form.:
C18H22ClNO
Mol. Mass.:
303.826
SMILES:
CC(COc1ccccc1)N(CCCl)Cc1ccccc1
Structure:
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