Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50295923
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
>5000±0 nM
Citation
 Schuehly, W; Paredes, JM; Kleyer, J; Huefner, A; Anavi-Goffer, S; Raduner, S; Altmann, KH; Gertsch, J Mechanisms of Osteoclastogenesis Inhibition by a Novel Class of Biphenyl-Type Cannabinoid CB(2) Receptor Inverse Agonists. Chem Biol 18:1053-64 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50295923
Synonyms:
4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-biphenyl-2-ol | CHEMBL549698 | Magreth-3a | Magreth-3b
Type:
Small organic molecule
Emp. Form.:
C19H20O2
Mol. Mass.:
280.3609
SMILES:
COc1ccc(cc1\C=C\C)-c1cc(CC=C)ccc1O
Structure:
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