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Target
Alpha-2C adrenergic receptor
Ligand
BDBM81772
Substrate
n/a
Ki
13±n/a nM
Comments
PDSP_327
Citation
 Bylund, DB; Blaxall, HS; Iversen, LJ; Caron, MG; Lefkowitz, RJ; Lomasney, JW Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. Mol Pharmacol 42:1-5 (1992) [PubMed] 
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
ADRA2C | adrenergic Alpha2C
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27257.01
Organism:
OK
Description:
adrenergic Alpha2C ADRA2C OK::G3GWB4
Residue:
230
Sequence:
MAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRSDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCKSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
  
Inhibitor
Name:
BDBM81772
Synonyms:
ARC-239 | CAS_122211 | NSC_122211
Type:
Small organic molecule
Emp. Form.:
C25H30N2O3
Mol. Mass.:
406.5173
SMILES:
COc1ccccc1N1CCN(CCC2C(=O)c3ccccc3C(C)(C)C2=O)CC1
Structure:
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