Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM55121
Substrate
n/a
Ki
2340±n/a nM
Comments
PDSP_728
Citation
 Sunahara, RK; Guan, HC; O'Dowd, BF; Seeman, P; Laurier, LG; Ng, G; George, SR; Torchia, J; Van Tol, HH; Niznik, HB Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature 350:614-9 (1991) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | DRD1_HUMAN | DRD1
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Human
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM55121
Synonyms:
cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | MLS000069419 | 3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)pyrocatechol;hydrochloride | US20240415800, Compound 2-7 (Dopamine)
Type:
Small organic molecule
Emp. Form.:
C8H11NO2
Mol. Mass.:
153.08
SMILES:
c1cc(c(cc1CCN)O)O
Structure:
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