Reaction Details Report a problem with these data
Target
D(1B) dopamine receptor
Ligand
BDBM55121
Substrate
n/a
Ki
228±n/a nM
Comments
PDSP_728
Citation
 Sunahara, RK; Guan, HC; O'Dowd, BF; Seeman, P; Laurier, LG; Ng, G; George, SR; Torchia, J; Van Tol, HH; Niznik, HB Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1. Nature 350:614-9 (1991) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
DOPAMINE D5 | dopamine receptor D5 | D(5) dopamine receptor | D1beta dopamine receptor | DRD5_HUMAN | DRD5 | DRD1B | DRD1L2
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Human
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM55121
Synonyms:
cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | MLS000069419 | 3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)pyrocatechol;hydrochloride | US20240415800, Compound 2-7 (Dopamine)
Type:
Small organic molecule
Emp. Form.:
C8H11NO2
Mol. Mass.:
153.08
SMILES:
c1cc(c(cc1CCN)O)O
Structure:
Search PDB for entries with ligand similarity: