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Target
Dopamine receptor D4
Ligand
BDBM55121
Substrate
n/a
Ki
28±n/a nM
Comments
PDSP_728
Citation
 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature 350:610-4 (1991) [PubMed]  Article 
Target
Name:
Dopamine receptor D4
Synonyms:
DOPAMINE D2 Long | DOPAMINE D4 | DRD2 | Dopamine receptor D4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43731.97
Organism:
CANINE
Description:
Q589Y6
Residue:
421
Sequence:
AGDADGLLAGRGPGAGTPGTPGAAAALAGGVLLIGAVLAGNALVCASVAAERALQTPTNYFIVSLAAADLLLALLVLPLFVYSEVQGGVWLFSPGLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLSYNRQGGGGRQLLLIGATWLLSAAVAAPVLCGLNDARGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARRAKLHGRTPRRPSGPGPPPPDGSPDGTPGPPPPDGSPDGTSDGTPGPPPPDGSPDGTPGPPPPDGSPDDNPRPPPPDSSPGPPPPEVTPDDTPDATPRPLPPAADAAAPPPADPAEPPRQPRKRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITRALCPACPVPPRLVSAVTWLGYVNSALNPLIYTVFNAEFRAVFRKA
  
Inhibitor
Name:
BDBM55121
Synonyms:
3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-aminoethyl)pyrocatechol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | Dopamine | MLS000069419 | SMR000059081 | cid_65340
Type:
Small organic molecule
Emp. Form.:
C8H11NO2
Mol. Mass.:
153.1784
SMILES:
NCCc1ccc(O)c(O)c1
Structure:
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