Reaction Details Report a problem with these data
Target
Carboxypeptidase B
Ligand
BDBM81909
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
8.2e+4±n/a nM
Citation
 Fernández, D; Avilés, FX; Vendrell, J Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design. Chem Biol Drug Des 73:75-82 (2009) [PubMed]  Article 
Target
Name:
Carboxypeptidase B
Synonyms:
CPB
Type:
Enzyme
Mol. Mass.:
48382.46
Organism:
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Description:
Q3T905
Residue:
429
Sequence:
MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREGVVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGGIHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGARRAGDLFRK
  
Inhibitor
Name:
BDBM81909
Synonyms:
N-benzyl-4-fluoro-N-((4-hydroxyquinazolin-2-yl)methylbenzensulfonamide, 9
Type:
Small organic molecule
Emp. Form.:
C22H18FN3O3S
Mol. Mass.:
423.46
SMILES:
Fc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)Cc1nc2ccccc2c(=O)[nH]1
Structure:
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