Reaction Details
Report a problem with these data
Report a problem with these dataTarget
kappa-type opioid receptor isoform 1
Ligand
BDBM224024
Substrate
n/a
Ki
12±n/a nM
Comments
PDSP_770
Citation
Benyhe, S; Varga, E; Hepp, J; Magyar, A; Borsodi, A; Wollemann, M Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation. Neurochem Res 15:899-904 (1990) [PubMed] Article More Info.:
Target
Name:
kappa-type opioid receptor isoform 1
Synonyms:
OPIATE Kappa | OPRK1 | Opioid receptor kappa 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44032.90
Organism:
Frog
Description:
F7A0F2
Residue:
392
Sequence:
MVMESPVQIFREEEAIIPERAPVGSTCSSSCAPACPSSCFPNTSWLLGWDDHDNVSAYPDLPLNEGNHTSISPTISVIITAVYSMVFVVGLVGNALVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTSFLMNSWPFGDVLCKIVVSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKCINICIWMLSSSVGISAIVLGGTKISDGSTECALQFPTHYWYWDTVMKMCVFIFAFIIPVFIITICYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIVCWTPIHIFVLVEALVDVPQSIAVVSIYYFCIALGYTNSSLNPILYAFLDENFKRCFKDFCFPSKHRLDRQPNSRVGNTVQDPACNRHGSQKPV
Inhibitor
Name:
BDBM224024
Synonyms:
BDBM50241435 | Dynorphin A (1-13) | YGGFLRRXRPKLK
Type:
Small organic molecule
Emp. Form.:
C75H126N24O15
Mol. Mass.:
1603.9547
SMILES:
[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O
Structure:
