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Target
kappa-type opioid receptor isoform 1
Ligand
BDBM81935
Substrate
n/a
Ki
36±n/a nM
Comments
PDSP_1351
Citation
 Benyhe, S; Varga, E; Hepp, J; Magyar, A; Borsodi, A; Wollemann, M Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation. Neurochem Res 15:899-904 (1990) [PubMed]  Article 
Target
Name:
kappa-type opioid receptor isoform 1
Synonyms:
OPIATE Kappa | OPRK1 | Opioid receptor kappa 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44032.90
Organism:
Frog
Description:
F7A0F2
Residue:
392
Sequence:
MVMESPVQIFREEEAIIPERAPVGSTCSSSCAPACPSSCFPNTSWLLGWDDHDNVSAYPDLPLNEGNHTSISPTISVIITAVYSMVFVVGLVGNALVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTSFLMNSWPFGDVLCKIVVSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKCINICIWMLSSSVGISAIVLGGTKISDGSTECALQFPTHYWYWDTVMKMCVFIFAFIIPVFIITICYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIVCWTPIHIFVLVEALVDVPQSIAVVSIYYFCIALGYTNSSLNPILYAFLDENFKRCFKDFCFPSKHRLDRQPNSRVGNTVQDPACNRHGSQKPV
  
Inhibitor
Name:
BDBM81935
Synonyms:
CAS_105618-26-6 | NSC_3034416 | Nor-BNI
Type:
Small organic molecule
Emp. Form.:
C40H43N3O6
Mol. Mass.:
661.7859
SMILES:
Oc1ccc2CC(C3CC3)N3CCC45C(Oc1c24)c1[nH]c2C4Oc6c7c(CC(C8CC8)N8CCC47C(O)(C8)Cc2c1CC5(O)C3)ccc6O |TLB:7:6:12.11:44.42,43:42:6.5.4.17:12.11,28:27:35.37:32.33,THB:23:24:35.37:32.33,45:25:35.37:32.33,41:42:6.5.4.17:12.11,16:17:12.11:44.42,3:4:12.11:44.42,36:35:32.33:25.24.26.27|
Structure:
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