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Target
kappa-type opioid receptor isoform 1
Ligand
BDBM50169774
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1935
Citation
 Benyhe, S; Varga, E; Hepp, J; Magyar, A; Borsodi, A; Wollemann, M Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation. Neurochem Res 15:899-904 (1990) [PubMed]  Article 
Target
Name:
kappa-type opioid receptor isoform 1
Synonyms:
OPIATE Kappa | OPRK1 | Opioid receptor kappa 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44032.90
Organism:
Frog
Description:
F7A0F2
Residue:
392
Sequence:
MVMESPVQIFREEEAIIPERAPVGSTCSSSCAPACPSSCFPNTSWLLGWDDHDNVSAYPDLPLNEGNHTSISPTISVIITAVYSMVFVVGLVGNALVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTSFLMNSWPFGDVLCKIVVSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKCINICIWMLSSSVGISAIVLGGTKISDGSTECALQFPTHYWYWDTVMKMCVFIFAFIIPVFIITICYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIVCWTPIHIFVLVEALVDVPQSIAVVSIYYFCIALGYTNSSLNPILYAFLDENFKRCFKDFCFPSKHRLDRQPNSRVGNTVQDPACNRHGSQKPV
  
Inhibitor
Name:
BDBM50169774
Synonyms:
2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; compound with methanesulfonic acid | CHEMBL360943 | U-50488H | U50,488H
Type:
Small organic molecule
Emp. Form.:
C19H26Cl2N2O
Mol. Mass.:
369.329
SMILES:
CN(C1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1
Structure:
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