Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2B
Ligand
BDBM50007871
Substrate
n/a
Ki
2600±n/a nM
Comments
PDSP_956
Citation
 McKenna, DJ; Peroutka, SJ Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J Neurosci 9:3482-90 (1989) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 2B
Synonyms:
5-HT2B | 5-hydroxytryptamine 2B receptor | HTR2B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15564.62
Organism:
BOVINE
Description:
Q8MI09
Residue:
137
Sequence:
KPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGFHKDKTLPNASADILMRRMSTVGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNVTLVLCDSCNQTTLNMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDA
  
Inhibitor
Name:
BDBM50007871
Synonyms:
CHEMBL8197 | ICS 205-930 | TROPISETRON
Type:
Small organic molecule
Emp. Form.:
C17H20N2O2
Mol. Mass.:
284.3529
SMILES:
CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 |THB:9:7:1:3.4|
Structure:
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