Reaction Details Report a problem with these data
Target
Alpha-1A adrenergic receptor
Ligand
BDBM36024
Substrate
n/a
Ki
901±n/a nM
Comments
PDSP_1482
Citation
 Jones, SB; Smith, JM; Jones, AW; Bylund, DB Alpha-1 adrenergic receptor binding in aortas from rat and dog: comparison of [3H]prazosin and beta-iodo-[125I]-4-hydroxyphenyl-ethyl-aminomethyl-tetralone. J Pharmacol Exp Ther 241:875-81 (1987) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_CANLF | ADRA1A | ADRA1C | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32268.65
Organism:
Dog
Description:
adrenergic Alpha1 0 Dog::O77621
Residue:
295
Sequence:
MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQITEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPVGGTGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG
  
Inhibitor
Name:
BDBM36024
Synonyms:
(R)-(-)-phenylephrine | PHENYLEPHRINE | Phenylephrine,(-)
Type:
Guest
Emp. Form.:
C9H14NO2
Mol. Mass.:
168.2124
SMILES:
C[NH2+]C[C@H](O)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: