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Target
Thromboxane A2 receptor
Ligand
BDBM81999
Substrate
n/a
Ki
31.8±n/a nM
Comments
PDSP_1746
Citation
 Hedberg, A; Hall, SE; Ogletree, ML; Harris, DN; Liu, EC Characterization of [5,6-3H]SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets. J Pharmacol Exp Ther 245:786-92 (1988) [PubMed] 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM81999
Synonyms:
CAS_3036123 | NSC_3036123 | SQ 28668
Type:
Small organic molecule
Emp. Form.:
C24H32O4
Mol. Mass.:
384.5085
SMILES:
CC(C(O)C=CC1C2CCC(O2)C1CC=CCCCC(O)=O)c1ccccc1 |w:4.3,14.15,TLB:5:6:8.9:11,THB:13:12:8.9:11|
Structure:
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