Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 5B
Ligand
BDBM35234
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1348
Citation
 Erlander, MG; Lovenberg, TW; Baron, BM; de Lecea, L; Danielson, PE; Racke, M; Slone, AL; Siegel, BW; Foye, PE; Cannon, K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A 90:3452-6 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5B
Synonyms:
5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41141.95
Organism:
RAT
Description:
5-HT5B 0 RAT::P35365
Residue:
370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
  
Inhibitor
Name:
BDBM35234
Synonyms:
DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradrenaline,(+) | [3H]NE
Type:
radiolabeled ligand
Emp. Form.:
C8H11NO3
Mol. Mass.:
169.1778
SMILES:
NCC(O)c1ccc(O)c(O)c1
Structure:
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