Reaction Details Report a problem with these data
Target
Glutamate metabotropic receptor 5
Ligand
BDBM50060133
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2019
Citation
 Joly, C; Gomeza, J; Brabet, I; Curry, K; Bockaert, J; Pin, JP Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. J Neurosci 15:3970-81 (1995) [PubMed] 
Target
Name:
Glutamate metabotropic receptor 5
Synonyms:
metabotropic glutamate 5a | metabotropic glutamate 5b
Type:
Enzyme Catalytic Domain
Mol. Mass.:
120646.45
Organism:
PORCINE
Description:
metabotropic glutamate 5a 0 PORCINE::H0VDS0
Residue:
1094
Sequence:
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISAEEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQHRFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMRKDYFDYINVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSVHINKKENLNQTAVIKPFPKSTESRGLGAGAGRRGGATGPTGGAGAASCAGAGPGGPEPPDAGAKALYDVAEGEEPFAAASVRPRSPSPISTLSQRAGSGGRTDDDVPSLHSEPAARSSSSQGSLMEQISSVVTSLSRANISELQLMMLSTGAPGPRGGRP
  
Inhibitor
Name:
BDBM50060133
Synonyms:
(1R,3R)-1-Amino-cyclopentane-1,3-dicarboxylic acid | 1-Amino-cyclopentane-1,3-dicarboxylic acid(cis-(1R,3R)-ACPD) | 1S, 3S-ACPD | CHEMBL107845
Type:
Small organic molecule
Emp. Form.:
C7H11NO4
Mol. Mass.:
173.1665
SMILES:
N[C@@]1(CC[C@H](C1)C(O)=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: