Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor
Ligand
BDBM86231
Substrate
n/a
Ki
0.28±n/a nM
Comments
PDSP_334
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor
Synonyms:
CHRM4 | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
53017.26
Organism:
RABBIT
Description:
Cholinergic, muscarinic M4 CHRM4 RABBIT::PPPPPP
Residue:
478
Sequence:
MANFTPVNGSSSNQSVRLVTSAHNRYETVEMVFIATVTGSLSLVTVVGNVLVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGQKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPMADKDTSNESSSGSATQNTKERPATELSTAEATTPAMSAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
  
Inhibitor
Name:
BDBM86231
Synonyms:
ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEMBL195 | NSC_3661 | US9333195, ATROPINE
Type:
Small organic molecule
Emp. Form.:
C17H23NO3
Mol. Mass.:
289.3694
SMILES:
CN1C2CCC1CC(C2)OC(=O)C(CO)c1ccccc1 |THB:9:7:1:3.4|
Structure:
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