Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M4
Ligand
BDBM82371
Substrate
n/a
Ki
8.32±n/a nM
Comments
PDSP_1918
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor M4
Synonyms:
CHRM4 | CHRM4 protein | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
30028.84
Organism:
bovine
Description:
A6QQE4
Residue:
271
Sequence:
MTVLYVHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPPGDTTARGELRNGKLEEAPPPVLPPPPRPMADKDTSNESSSGSATQNTKERPPTELSTTEATTPATPAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARSQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPETVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
  
Inhibitor
Name:
BDBM82371
Synonyms:
CAS_1508-75-4 | NSC_5593 | TROPICAMIDE
Type:
Small organic molecule
Emp. Form.:
C17H20N2O2
Mol. Mass.:
284.3529
SMILES:
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1
Structure:
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