Reaction Details Report a problem with these data
Target
Cholecystokinin
Ligand
BDBM82386
Substrate
n/a
Ki
1100±n/a nM
Comments
PDSP_16
Citation
 Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A 83:4918-22 (1986) [PubMed]  Article 
Target
Name:
Cholecystokinin
Synonyms:
CCKN_RAT | Cck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12844.29
Organism:
RAT
Description:
Cholecystokinin 0 RAT::P01355
Residue:
115
Sequence:
MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGALLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
  
Inhibitor
Name:
BDBM82386
Synonyms:
CCK antagonist synthetic 15
Type:
n/a
Emp. Form.:
C25H19FN4O2
Mol. Mass.:
426.4424
SMILES:
Cc1ccc2c(c[nH]c2c1)C(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O |t:16|
Structure:
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