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Target
GABA(A) receptor-associated protein
Ligand
BDBM50019808
Substrate
n/a
Ki
800±n/a nM
Comments
PDSP_9
Citation
 Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A 83:4918-22 (1986) [PubMed]  Article 
Target
Name:
GABA(A) receptor-associated protein
Synonyms:
GABA A Benzodiazepine | GABA-A receptor subunit alpha 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13921.89
Organism:
GUINEA PIG
Description:
D7RA28
Residue:
117
Sequence:
MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
  
Inhibitor
Name:
BDBM50019808
Synonyms:
(R)6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-methyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene | CCK antagonist synthetic 12 | CHEMBL278777
Type:
Small organic molecule
Emp. Form.:
C26H20FN5
Mol. Mass.:
421.4689
SMILES:
Cc1nnc2C(Cc3c[nH]c4ccccc34)N=C(c3ccccc3F)c3ccccc3-n12 |t:18|
Structure:
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