Reaction Details Report a problem with these data
Target
Somatostatin receptor type 3
Ligand
BDBM82464
Substrate
n/a
Ki
22.90±n/a nM
Comments
PDSP_1591
Citation
 Hoyer, D; Lübbert, H; Bruns, C Molecular pharmacology of somatostatin receptors. Naunyn Schmiedebergs Arch Pharmacol 350:441-53 (1994) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS3R | SSR-28 | SSR3_MOUSE | Smstr3 | Somatostatin receptor | Somatostatin receptor 3 | Somatostatin receptor type 3 | Sstr3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47225.49
Organism:
MOUSE
Description:
SOMATOSTATIN SST3 SSTR3 MOUSE::P30935
Residue:
428
Sequence:
MATVTYPSSEPTTLDPGNASSTWPLDTTLGNTSAGASLTGLAVSGILISLVYLVVCVVGLLGNSLVIYVVLRHTSSPSVTSVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRTAFIIYTAALGFFGPLLVICLCYLLIVVKVRSTTRRVRAPSCQWVQAPACQRRRRSERRVTRMVVAVVALFVLCWMPFYLLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRILLRPSRRIRSQEPGSGPPEKTEEEEDEEEEERREEEERRMQRGQEMNGRLSQIAQAGTSGQQPRPCTGTAKEQQLLPQEATAGDKASTLSHL
  
Inhibitor
Name:
BDBM82464
Synonyms:
CAS_71306 | NSC_71306 | RC 160 | Vapreotide
Type:
Small organic molecule
Emp. Form.:
C57H70N12O9S2
Mol. Mass.:
1131.371
SMILES:
CC(C)C1NC(=O)C(CCCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CSSCC(NC1=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)C(N)Cc1ccccc1
Structure:
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