Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM82513
Substrate
n/a
Ki
121±n/a nM
Comments
PDSP_986
Citation
 D'Angelo, DD; Davis, MG; Ali, S; Dorn, GW Cloning and pharmacologic characterization of a thromboxane A2 receptor from K562 (human chronic myelogenous leukemia) cells. J Pharmacol Exp Ther 271:1034-41 (1994) [PubMed] 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM82513
Synonyms:
CAS_122979 | I-PTA-OH | NSC_122979
Type:
Small organic molecule
Emp. Form.:
C25H36INO4
Mol. Mass.:
541.4621
SMILES:
CC1(C)C2CC1C(CC=CCCCC(O)=O)C(C2)NCC(O)Cc1ccc(O)c(I)c1 |w:8.8,THB:7:6:1:4,18:16:1:4|
Structure:
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