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Target
Alpha-2A adrenergic receptor
Ligand
BDBM30993
Substrate
n/a
Ki
653±n/a nM
Comments
PDSP_1589
Citation
 O'Rourke, MF; Iversen, LJ; Lomasney, JW; Bylund, DB Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors. J Pharmacol Exp Ther 271:735-40 (1994) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADA2A_BOVIN | ADRA2A | Alpha-2A adrenergic receptor | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | Alpha-2Da adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2D
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49275.13
Organism:
BOVINE
Description:
adrenergic Alpha2 0 BOVINE::Q28838
Residue:
452
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM30993
Synonyms:
Ajmalicine | MLS000111555 | Raubasine | SMR000107477 | cid_251561
Type:
Small organic molecule
Emp. Form.:
C21H24N2O3
Mol. Mass.:
352.4269
SMILES:
COC(=O)C1=COC(C)C2CN3CCc4c([nH]c5ccccc45)C3CC12 |t:4|
Structure:
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