Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50034179
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2591
Citation
 van Galen, PJ; van Bergen, AH; Gallo-Rodriguez, C; Melman, N; Olah, ME; IJzerman, AP; Stiles, GL; Jacobson, KA A binding site model and structure-activity relationships for the rat A3 adenosine receptor. Mol Pharmacol 45:1101-11 (1994) [PubMed] 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50034179
Synonyms:
2-(6-Amino-8-bromo-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | 2-(6-amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | 8-Bromoadenosine | CHEMBL440836 | ChEMBL_20304
Type:
Small organic molecule
Emp. Form.:
C10H12BrN5O4
Mol. Mass.:
346.137
SMILES:
Nc1ncnc2n(C3OC(CO)C(O)C3O)c(Br)nc12
Structure:
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