Reaction Details Report a problem with these data
Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM82655
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
8030±604 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM82655
Synonyms:
4-[2-(2-hydroxybenzoyl)carbohydrazonoyl]phenyl benzoate | MLS000541089 | SMR000161874 | [4-[[(2-hydroxybenzoyl)hydrazinylidene]methyl]phenyl] benzoate | [4-[[(2-hydroxyphenyl)carbonylhydrazinylidene]methyl]phenyl] benzoate | benzoic acid [4-[(salicyloylhydrazono)methyl]phenyl] ester | benzoic acid [4-[[[(2-hydroxyphenyl)-oxomethyl]hydrazinylidene]methyl]phenyl] ester | cid_1237334
Type:
Small organic molecule
Emp. Form.:
C21H16N2O4
Mol. Mass.:
360.3627
SMILES:
Oc1ccccc1C(=O)NN=Cc1ccc(OC(=O)c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: