Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM80031
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
9500±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80031
Synonyms:
MLS001002995 | N-(4-morpholin-4-ylsulfonylphenyl)-2-quinolin-8-ylsulfanyl-ethanamide | N-(4-morpholin-4-ylsulfonylphenyl)-2-quinolin-8-ylsulfanylacetamide | N-(4-morpholinosulfonylphenyl)-2-(8-quinolylthio)acetamide | N-[4-(4-morpholinylsulfonyl)phenyl]-2-(8-quinolinylthio)acetamide | SMR000372646 | cid_4261263
Type:
Small organic molecule
Emp. Form.:
C21H21N3O4S2
Mol. Mass.:
443.539
SMILES:
O=C(CSc1cccc2cccnc12)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: