Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM80006
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
9410±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80006
Synonyms:
2,5-diphenyl-N'-(phenylcarbonyl)pyrazole-3-carbohydrazide | MLS000388665 | N'-benzoyl-2,5-diphenyl-3-pyrazolecarbohydrazide | N'-benzoyl-2,5-diphenyl-pyrazole-3-carbohydrazide | N'-benzoyl-2,5-diphenylpyrazole-3-carbohydrazide | SMR000254838 | cid_4883406
Type:
Small organic molecule
Emp. Form.:
C23H18N4O2
Mol. Mass.:
382.4146
SMILES:
O=C(NNC(=O)c1ccccc1)c1cc(nn1-c1ccccc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: