Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 6
Ligand
BDBM80072
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
9030±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80072
Synonyms:
(6E)-6-[1-(2-quinolin-2-ylhydrazinyl)ethylidene]cyclohexa-2,4-dien-1-one | (6E)-6-[1-(2-quinolinylhydrazo)ethylidene]-1-cyclohexa-2,4-dienone | (6E)-6-[1-[N'-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | (6Z)-6-[1-[N''-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | (6Z)-6-[1-[N'-(2-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one | MLS002702053 | SMR001565625 | cid_5383429
Type:
Small organic molecule
Emp. Form.:
C17H15N3O
Mol. Mass.:
277.3205
SMILES:
CC(N=Nc1ccc2ccccc2n1)c1ccccc1O |w:2.1|
Structure:
Search PDB for entries with ligand similarity: