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Target
Beta-lactamase
Ligand
BDBM63203
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
>49748±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM63203
Synonyms:
2-[2-[(Z)-2-nitroethenyl]phenoxy]acetic acid ethyl ester | 2-[2-[(Z)-2-nitrovinyl]phenoxy]acetic acid ethyl ester | MLS000586023 | SMR000204386 | cid_5286552 | ethyl 2-[2-[(Z)-2-nitroethenyl]phenoxy]acetate | ethyl 2-[2-[(Z)-2-nitroethenyl]phenoxy]ethanoate | ethyl {2-[(Z)-2-nitrovinyl]phenoxy}acetate
Type:
Small organic molecule
Emp. Form.:
C12H13NO5
Mol. Mass.:
251.2353
SMILES:
CCOC(=O)COc1ccccc1\C=C/[N+]([O-])=O
Structure:
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