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Target
Delta-type opioid receptor
Ligand
BDBM83458
Substrate
n/a
Meas. Tech.
Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay
EC50
>92454±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay (2011)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM83458
Synonyms:
1-[2-[2-(1-oxo-2-triphenylphosphoranylideneethyl)phenyl]phenyl]-2-triphenylphosphoranylideneethanone | 2-(triphenyl--phosphanylidene)-1-[2-[2-[2-(triphenyl--phosphanylidene)acetyl]phenyl]phenyl]ethanone | 2-(triphenyl--phosphanylidene)-1-[2-[2-[2-(triphenyl--phosphanylidene)ethanoyl]phenyl]phenyl]ethanone | 2-triphenylphosphoranylidene-1-[2-[2-(2-triphenylphosphoranylideneacetyl)phenyl]phenyl]ethanone | MLS002702210 | SMR001565773 | cid_381571
Type:
Small organic molecule
Emp. Form.:
C52H40O2P2
Mol. Mass.:
758.8203
SMILES:
O=C(C=P(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1-c1ccccc1C(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: