Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83584
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
>99000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83584
Synonyms:
MLS000703092 | N-(3-{3-[4-(dimethylamino)phenyl]acryloyl}phenyl)acetamide | N-[3-[(E)-3-[4-(dimethylamino)phenyl]-1-oxoprop-2-enyl]phenyl]acetamide | N-[3-[(E)-3-[4-(dimethylamino)phenyl]acryloyl]phenyl]acetamide | N-[3-[(E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl]phenyl]acetamide | N-[3-[(E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl]phenyl]ethanamide | SMR000229308 | cid_5794211
Type:
Small organic molecule
Emp. Form.:
C19H20N2O2
Mol. Mass.:
308.3743
SMILES:
CN(C)c1ccc(\C=C\C(=O)c2cccc(NC(C)=O)c2)cc1
Structure:
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