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Target
Beta-2 adrenergic receptor
Ligand
BDBM84229
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset1
EC50
19.95±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from Powderset1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84229
Synonyms:
2-(4-tert-butylphenoxy)-N-(4-[1,3]oxazolo[5,4-b]pyridin-2-ylphenyl)acetamide | 2-(4-tert-butylphenoxy)-N-(4-oxazolo[5,4-b]pyridin-2-ylphenyl)acetamide | 2-(4-tert-butylphenoxy)-N-[4-(2-oxazolo[5,4-b]pyridinyl)phenyl]acetamide | 2-(4-tert-butylphenoxy)-N-[4-([1,3]oxazolo[5,4-b]pyridin-2-yl)phenyl]acetamide | 2-(4-tert-butylphenoxy)-N-[4-([1,3]oxazolo[5,4-b]pyridin-2-yl)phenyl]ethanamide | MLS000533881 | SMR000141318 | cid_1369799
Type:
Small organic molecule
Emp. Form.:
C24H23N3O3
Mol. Mass.:
401.4577
SMILES:
CC(C)(C)c1ccc(OCC(=O)Nc2ccc(cc2)-c2nc3cccnc3o2)cc1
Structure:
Search PDB for entries with ligand similarity: