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Target
Platelet-activating factor receptor
Ligand
BDBM50000703
Substrate
n/a
Meas. Tech.
ChEBML_155155
Ki
16900±n/a nM
Citation
 Guinn, DE; Summers, JB; Heyman, HR; Conway, RG; Rhein, DA; Albert, DH; Magoc, T; Carter, GW Synthesis and structure-activity relationships of a series of novel benzopyran-containing platelet activating factor antagonists. J Med Chem 35:2055-61 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50000703
Synonyms:
7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methoxy-10,10-dimethyl-2,3,4,10-tetrahydro-1H-9-oxa-3-aza-phenanthrene | CHEMBL62322
Type:
Small organic molecule
Emp. Form.:
C26H32FNO2
Mol. Mass.:
409.5362
SMILES:
COc1cc(cc2OC(C)(C)C3=C(CNCC3)c12)C(C)CCCc1ccc(F)cc1 |t:11|
Structure:
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