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Target
Adenosine receptor A3
Ligand
BDBM50240842
Substrate
n/a
Meas. Tech.
ChEMBL_1669078 (CHEMBL4018966)
Ki
2.7±n/a nM
Citation
 Xia, L; Burger, WAC; van Veldhoven, JPD; Kuiper, BJ; van Duijl, TT; Lenselink, EB; Paasman, E; Heitman, LH; IJzerman, AP Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A J Med Chem 60:7555-7568 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50240842
Synonyms:
CHEMBL4093013
Type:
Small organic molecule
Emp. Form.:
C22H22N4O3
Mol. Mass.:
390.4351
SMILES:
COc1ccn2c(c1)nc1n(Cc3ccccc3)c(=O)n(CC3CCC3)c(=O)c21
Structure:
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