Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50163864
Substrate
n/a
Meas. Tech.
ChEMBL_1673908 (CHEMBL4023937)
KOFF
0.65 s-1
Citation
 Linkuvienė, V; Talibov, VO; Danielson, UH; Matulis, D Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. J Med Chem 61:2292-2302 (2018) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) | CAH7_HUMAN | CA7 | Carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Human
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50163864
Synonyms:
3-(1H-benzimidazol-1-ylacetyl)benzenesulfonamide (3a) | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 3 | CHEMBL3799296
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3S
Mol. Mass.:
315.07
SMILES:
NS(=O)(=O)c1cccc(c1)C(=O)Cn1cnc2ccccc12
Structure:
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